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Pharmacology · chapter 38 · Ophthalmic Drugs

Introduction to the Eyes

The 14 things this section of the textbook says that you are most likely to be asked about — quoted word for word, not retold. Then 6 practice questions with the reasoning.

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Key points

  1. Pupil size is a key assessment

    The iris controls the size of the pupil based on the amount of light. This is an essential nursing assessment because deviations from normal size or unequal size pupils can indicate pathology.
  2. Intraocular pressure

    Intraocular pressure (IOP) is the fluid pressure caused by the amount of aqueous humor in the anterior chamber. A normal IOP is 10–21 mm Hg (Begum, 2023).
  3. High and low IOP are both harmful

    Untreated elevated IOP can lead to blindness. Abnormally low IOP, known as hypotony, can lead to eye wasting.
  4. Why topical eye drugs are used

    These drugs are intended for direct administration into the conjunctiva of the eye. This route limits systemic absorption, thereby decreasing the risk of adverse effects.
  5. What glaucoma is

    Glaucoma is a group of diseases characterized by a decrease in peripheral vision due to an obstruction of aqueous humor that increases IOP, which can damage the optic nerve.
  6. Who is at higher risk

    Also at higher risk are clients older than 40 years, those with thinner corneas, those with chronic eye inflammation, and those taking medications that are known to increase eye pressure (Boyd, 2022b).
  7. Anxiety can raise the IOP reading

    The nurse should be aware that a client’s anxiety can artificially increase an IOP reading.
  8. Open-angle glaucoma is silent

    Open-angle glaucoma occurs when the trabecular meshwork becomes occluded and cannot drain the continuous production of aqueous humor. Often there are no early symptoms.
  9. Closed-angle glaucoma is sudden

    Closed-angle glaucoma progresses suddenly with a sudden rise in IOP. Clients can become blind with little warning.
  10. Symptoms of closed-angle glaucoma

    IOP increases rapidly to dangerous levels when the angle between the cornea and iris becomes significantly narrowed. Symptoms can include sudden headache, eye pain, and/or blurred vision.
  11. Keratitis is an emergency

    Keratitis is considered a medical emergency. The client will need a timely diagnosis and treatment plan because extensive ulceration can lead to blindness.
  12. Press the inner corner after drops

    Apply gentle pressure to the corner of the eye where the upper and lower lids meet closest to the nose for 30–60 seconds to prevent systemic absorption.
  13. Waiting between drops

    The client should wait at least 2 minutes between drops if needing to administer more than one drop of the same medication; they should wait at least 5 minutes between drugs if a different ocular medication is prescribed.
  14. Drops before ointment

    It is crucial the drops are instilled first. The client should then wait 5–10 minutes before applying the ointment.

Terms to know

Aqueous humor
Anterior chamber: Located between the back of the cornea and front of the lens, this chamber contains aqueous humor, which is the tissue fluid of the eye.
Hypotony
Abnormally low IOP, known as hypotony, can lead to eye wasting.
Myopia
Myopia, referred to as nearsightedness, is characterized by seeing distant objects out of focus; however, close objects are clearly seen.
Presbyopia
Presbyopia occurs as the eye ages and is characterized by lens thickening and loss of elasticity.
Uveitis
Uveitis is an inflammation of the middle part of the eye called the uvea.
Keratoconjunctivitis sicca
Keratoconjunctivitis sicca is dryness of the conjunctiva and cornea.

Practice questions

Stuck on select-all-that-apply? How to take them one option at a time.

The graded version needs JavaScript. Every question is below anyway, with the answer and why.

Every question here, with the answer

  1. A client arrives in the emergency department with sudden eye pain, a severe headache and blurred vision. Which condition should the nurse suspect?

    1. Closed-angle glaucoma
    2. Presbyopia
    3. Open-angle glaucoma
    4. Dry macular degeneration

    Answer: Closed-angle glaucoma

    Closed-angle glaucoma causes a sudden rise in IOP, with symptoms such as sudden headache, eye pain and blurred vision, and can cause blindness with little warning. Open-angle glaucoma often has no early symptoms, and presbyopia and dry macular degeneration are gradual.

  2. The nurse is teaching a client to instill glaucoma eye drops. What should the client do right after instilling the drop to prevent systemic absorption?

    1. Rub the eye gently to spread the medication.
    2. Rinse the dropper with tap water.
    3. Blink rapidly for one minute.
    4. Press gently on the inner corner of the eye near the nose for 30–60 seconds.

    Answer: Press gently on the inner corner of the eye near the nose for 30–60 seconds.

    Gentle pressure at the inner corner of the eye for 30–60 seconds prevents systemic absorption. Clients should not rub their eyes after administration or rinse the eyedropper.

  3. A client is prescribed an eye drop and an eye ointment for the same eye. Which instruction is correct?

    1. Apply the ointment first, then the drops immediately.
    2. Mix the drops into the ointment before applying.
    3. Instill the drops first, then wait 5–10 minutes before the ointment.
    4. Apply both at the same moment.

    Answer: Instill the drops first, then wait 5–10 minutes before the ointment.

    Drops must be instilled first, followed by a 5–10 minute wait before the ointment. In reverse order the ointment may be washed away and be ineffective.

  4. A nurse is teaching a client how to use eye drops at home. Which statements by the client show correct understanding? Select all that apply.

    1. "I will check the expiration date before using the drops."
    2. "I will rinse the dropper after each use."
    3. "I will wait at least 5 minutes before using a different eye drop."
    4. "I will not let the dropper touch my eye."
    5. "I can use the drops if they have changed color."

    Answer: "I will check the expiration date before using the drops.", "I will wait at least 5 minutes before using a different eye drop.", "I will not let the dropper touch my eye."

    Clients should check the expiration date, keep the dropper from touching the eye or any surface, and wait at least 5 minutes between different eye drugs. They should not rinse the eyedropper or use drops that have changed color.

  5. During glaucoma screening, a client is very anxious about the tonometer touching the eye. How can this affect the result?

    1. Anxiety has no effect on IOP readings.
    2. Anxiety causes the cornea to become thinner.
    3. Anxiety can artificially increase the IOP reading.
    4. Anxiety makes the IOP reading falsely low.

    Answer: Anxiety can artificially increase the IOP reading.

    A client's anxiety can artificially increase an IOP reading, so the nurse acknowledges the worry and explains that a numbing drop is used. The other options are not supported by the section.

  6. Which clients have a higher risk for glaucoma? Select all that apply.

    1. A client taking medication known to increase eye pressure
    2. A client with chronic eye inflammation
    3. A 55-year-old client
    4. A 25-year-old client with myopia and no other risk factors
    5. A client with thinner corneas

    Answer: A client taking medication known to increase eye pressure, A client with chronic eye inflammation, A 55-year-old client, A client with thinner corneas

    Higher risk includes clients older than 40, those with thinner corneas, chronic eye inflammation, or medications that increase eye pressure. A young client with only myopia has none of these listed risk factors.

Where every quote comes from

Section 38.1 Introduction to the Eyes of Pharmacology for Nurses by Tina Barbour-Taylor, Leah Mueller (Sabato), Donna Paris, Dorie Weaver, OpenStax, 2024. Read the whole section free at openstax.org.

The textbook is licensed under CC BY-NC-SA 4.0. This page quotes it word for word and adds the headings, the order and the practice questions; references to the book's figures and stray spaces left by its formatting are removed. The page is shared under the same licence. Nothing here is sold.