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Pharmacology · chapter 18 · Antihypertensive and Antianginal Drugs

Hypertension and Angina

The 14 things this section of the textbook says that you are most likely to be asked about — quoted word for word, not retold. Then 6 practice questions with the reasoning.

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Key points

  1. What determines blood pressure

    The two elements that determine blood pressure are cardiac output and peripheral vascular resistance. Cardiac output (CO) is the volume of blood pumped by the heart per unit of time, usually measured in liters per minute.
  2. Systolic and diastolic readings

    The systolic blood pressure reading represents the amount of pressure within the arteries when the heart contracts, whereas the diastolic blood pressure reading reflects the amount of pressure when the heart is at rest between beats.
  3. What hypertension is

    Hypertension occurs when an individual’s blood pressure is above normal limits for a sustained period of time. Hypertension can be either primary (essential) hypertension or secondary hypertension.
  4. Primary hypertension and its risk factors

    Primary hypertension is caused by unknown elements; however, some studies have implicated genetics and behavioral and environmental factors, including age, high salt intake, insulin resistance, obesity, high alcohol intake, sedentary lifestyle, smoking, and stress (Aggarwal et al., 2023; Iqbal Jamal, 2022).
  5. Secondary hypertension

    Secondary hypertension results from other conditions involving the central nervous system, endocrine system, and renal system and is treated along with the underlying condition. Secondary hypertension may be cured if the treatment for the underlying condition is successful.
  6. Vasopressin raises blood pressure

    Vasopressin is an antidiuretic hormone that regulates reabsorption of water by the kidneys; it is released by the pituitary gland in response to low blood volume. Vasopressin causes retention of body fluids, vasoconstriction, and increased blood pressure.
  7. Normal blood pressure

    Normal blood pressure is a systolic reading of less than 120 mm Hg and a diastolic reading of less than 80 mm Hg.
  8. Often silent, then these symptoms

    Symptoms of hypertension may not occur for years, and most of the time, the symptoms can be silent. Symptoms typically associated with hypertension include elevated blood pressure readings, headaches, dizziness, nausea, vomiting, visual disturbances, and neurological disturbances such as disorientation or a decreased level of consciousness.
  9. Low-sodium diet

    Clients with hypertension should eat a low-sodium diet consisting of whole grains, vegetables, and fruits.
  10. Some activity beats none

    If the client cannot do 30–40 minutes of moderate exercise four times a week, the nurse should suggest an alternate exercise plan, emphasizing that some physical activity is better than no physical activity.
  11. Primary antihypertensive drug classes

    Angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, beta-adrenergic blockers, calcium channel blockers, and thiazide-like diuretics (Khalil Zeltser, 2022) are the primary antihypertensive drugs used to treat high blood pressure.
  12. What angina is

    Angina (also called angina pectoris) is characterized by discomfort in the front of the chest, neck, shoulders, jaw, or arms that is precipitated by physical exertions and relieved by rest within 5 minutes or sublingual nitrates (Ueng et al., 2023).
  13. Unstable angina is an emergency

    Unstable angina is unpredictable and considered a medical emergency. Unlike stable angina, unstable angina usually occurs during rest and does not follow a pattern of similar episodes of chest pain; episodes may last longer than stable angina episodes.
  14. First-line drugs for angina

    Nitrates are the first line of treatment for angina along with beta-adrenergic blockers and calcium channel blockers (Rousan Thadani, 2019).

Terms to know

Cardiac output
Cardiac output (CO) is the volume of blood pumped by the heart per unit of time, usually measured in liters per minute.
Hypertension
Hypertension occurs when an individual’s blood pressure is above normal limits for a sustained period of time.
Vasopressin
Vasopressin is an antidiuretic hormone that regulates reabsorption of water by the kidneys; it is released by the pituitary gland in response to low blood volume.
Variant (Prinzmetal) angina
Variant (Prinzmetal) angina, unlike the other forms of angina, is not caused by coronary artery disease but rather by a spasm in the heart’s arteries that temporarily decreases blood flow and almost always occurs at rest.
Microvascular angina
Microvascular angina is frequent episodes of angina that occur due to coronary microvascular disease.

Practice questions

Stuck on select-all-that-apply? How to take them one option at a time.

The graded version needs JavaScript. Every question is below anyway, with the answer and why.

Every question here, with the answer

  1. A client with a blood pressure of 150/94 mm Hg at three visits says, "I feel fine, so I can't have high blood pressure." What is the nurse's best response?

    1. Your readings are normal for your age.
    2. Hypertension often has no symptoms for years, so regular checks matter.
    3. You only need treatment once you feel dizzy.
    4. You are right; hypertension always causes headaches.

    Answer: Hypertension often has no symptoms for years, so regular checks matter.

    Symptoms of hypertension may not occur for years and are often silent, so feeling well does not rule it out. The readings are above normal, and waiting for symptoms delays treatment while organ damage can develop.

  2. A client with a history of stable angina calls the clinic and says chest pain started while resting on the couch, does not follow his usual pattern, and has lasted longer than usual. How should the nurse interpret this?

    1. A normal response to the client's medication
    2. Typical stable angina that will pass with rest
    3. Possible unstable angina, which is a medical emergency
    4. Microvascular angina that needs no urgent care

    Answer: Possible unstable angina, which is a medical emergency

    Unstable angina is unpredictable, usually occurs at rest, does not follow a pattern, and may last longer; it is a medical emergency. Stable angina is predictable and follows a pattern, so this picture does not fit it.

  3. A client with hypertension says she cannot manage 30–40 minutes of exercise four times a week because of her work schedule. What should the nurse do?

    1. Advise her to rely on medication instead of exercise.
    2. Tell her to exercise only on weekends for several hours.
    3. Tell her exercise will not help unless she does the full amount.
    4. Suggest an alternate exercise plan and explain that some activity is better than none.

    Answer: Suggest an alternate exercise plan and explain that some activity is better than none.

    When a client cannot meet the recommended amount, the nurse suggests an alternate exercise plan and emphasizes that some physical activity is better than none. Dismissing exercise or replacing it with medication is not supported by the section.

  4. A client is diagnosed with variant (Prinzmetal) angina. Which explanation of the cause is accurate?

    1. Low blood pressure after meals
    2. Coronary artery disease blocking blood flow during exercise
    3. A spasm in the heart's arteries that temporarily decreases blood flow, usually at rest
    4. Disease of the heart valves

    Answer: A spasm in the heart's arteries that temporarily decreases blood flow, usually at rest

    Variant (Prinzmetal) angina is not caused by coronary artery disease but by a spasm in the heart's arteries that temporarily decreases blood flow and almost always occurs at rest. The other options describe other causes.

  5. A nurse is planning lifestyle teaching for a client newly diagnosed with primary hypertension. Which changes should the nurse include? Select all that apply.

    1. Increased physical activity
    2. Adding salt to replace fluid lost through sweating
    3. Smoking cessation
    4. Reduced alcohol intake
    5. Diet modification with less sodium

    Answer: Increased physical activity, Smoking cessation, Reduced alcohol intake, Diet modification with less sodium

    Nonpharmacologic treatment includes diet modification with a low-sodium diet, more physical activity, smoking cessation, and reduced alcohol intake. Adding salt goes against the low-sodium recommendation.

  6. Which findings would the nurse recognise as symptoms associated with hypertension? Select all that apply.

    1. Decreased level of consciousness
    2. Headaches
    3. Increased appetite
    4. Visual disturbances
    5. Productive cough with fever

    Answer: Decreased level of consciousness, Headaches, Visual disturbances

    Symptoms associated with hypertension include headaches, dizziness, nausea, vomiting, visual disturbances, and neurological disturbances such as a decreased level of consciousness. Increased appetite and a productive cough with fever are not listed.

Where every quote comes from

Section 18.1 Hypertension and Angina of Pharmacology for Nurses by Tina Barbour-Taylor, Leah Mueller (Sabato), Donna Paris, Dorie Weaver, OpenStax, 2024. Read the whole section free at openstax.org.

The textbook is licensed under CC BY-NC-SA 4.0. This page quotes it word for word and adds the headings, the order and the practice questions; references to the book's figures and stray spaces left by its formatting are removed. The page is shared under the same licence. Nothing here is sold.