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Pharmacology · chapter 3 · Ethics, Legal Considerations, and Safety

Drug Errors and Prevention

The 14 things this section of the textbook says that you are most likely to be asked about — quoted word for word, not retold. Then 6 practice questions with the reasoning.

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Key points

  1. Drug error significance

    Drug errors are a significant cause of morbidity and mortality in the United States.
  2. Medication error pathway

    A medication error is “an error (of commission or omission) at any step along the pathway that begins when a clinician prescribes a medication and ends when the patient actually takes the drug” (Agency for Healthcare Research and Quality [AHRQ], 2019b, para. 1).
  3. Owning medication errors

    Being honest and owning up to a medication error is not only “right” but also may save the life of the client if an intervention can prevent a bad outcome.
  4. Ethical principles framework

    Remembering the ethical principles of autonomy, beneficence, nonmaleficence, justice, veracity (truth), and confidentiality will provide a framework for the nurse as these conflicts arise.
  5. Informed consent requirements

    According to Varkey (2021, p. 19), “the requirements of an informed consent for a medical or surgical procedure, or for research, are that the client or subject (i) must be competent to understand and decide, (ii) receives a full disclosure, (iii) comprehends the disclosure, (iv) acts voluntarily, and (v) consents to the proposed action.”
  6. Medication refusal rights

    Within the setting of medication administration, autonomy means clients have the right to refuse a drug that has been ordered for them.
  7. Benefit–risk before administration

    Before any drug is ordered by the provider, the benefit of the drug versus the risk of the drug is considered. Before any drug is administered to a client, the benefit of the drug versus the risk of the drug is again weighed.
  8. Ongoing benefit–risk monitoring

    After drug therapy begins, the client is monitored to complete an ongoing evaluation of the benefit–risk balance. Ideally, the drug therapy continues as long as it is thought that the benefits outweigh the risks.
  9. Sentinel event harm

    A sentinel event is defined by The Joint Commission (TJC) (n.d.-b) as “a patient safety event that results in death, permanent harm, or severe temporary harm.”
  10. Sentinel event response

    An institution accredited by TJC must have policies in place to investigate and respond to sentinel events. The root cause analysis is helpful in identifying the underlying factors related to the harmful event and developing a plan to prevent another event.
  11. ADRs versus medication errors

    These drug reactions affect the safety of the client but are not due to a medication error on the part of a health care provider.
  12. Reporting adverse drug reactions

    It is important for the nurse to report adverse drug reactions. The U.S. Food and Drug administration (FDA) has a reporting mechanism in place through a portal called MedWatch for individuals (health care providers or consumers) to voluntarily report any adverse drug event.
  13. Medication errors are preventable

    Medication errors, however, are preventable. If a physician orders an incorrect dose of a medication but the pharmacist catches the mistake before dispensing it, it is considered a medication error.
  14. Nurse as final safeguard

    There are many different ways for an error to occur, but in the clinical setting, the nurse is the final person in the chain able to prevent an error from occurring.

Terms to know

medication error
According to the National Coordinating Council for Medication Error Reporting and Prevention (2023), a medication error is defined as “any preventable event that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of the health care professional, patient, or consumer.”
Autonomy
Autonomy in medicine essentially means having the right to make one’s own health care decisions, being independent, and having control over oneself.
Beneficence
Beneficence is a principle that requires nurses to “do good” to actively promote their clients’ health and well-being.
nonmaleficence
The principle of beneficence extends to nonmaleficence, which requires that nurses do no harm to the client and do all they can to safeguard a client from harm.
benefit–risk assessment
The benefit–risk assessment is the analysis of the benefits and risks associated with a drug (Kürzinger et al., 2020).
sentinel event
A sentinel event is defined by The Joint Commission (TJC) (n.d.-b) as “a patient safety event that results in death, permanent harm, or severe temporary harm.”
adverse drug reaction (ADR)
The World Health Organization (n.d., p. 1) defines an adverse drug reaction (ADR) as “harmful, unintended reactions to medicines that occur at doses normally used for treatment.”
adverse drug event (ADE)
An adverse drug event (ADE) is client harm resulting from exposure to a drug.

Practice questions

Stuck on select-all-that-apply? How to take them one option at a time.

The graded version needs JavaScript. Every question is below anyway, with the answer and why.

Every question here, with the answer

  1. A nurse realizes that a medication was administered to the wrong client. The client is currently stable. Which action best reflects ethical nursing practice described in this section?

    1. Monitor the client until the end of the shift before deciding whether to report the error.
    2. Ask another nurse to assess the client without explaining that a medication error occurred.
    3. Tell the charge nurse and provider promptly, state that a mistake occurred, and ask how to solve the problem.
    4. Document the medication as given correctly because the client has no symptoms.

    Answer: Tell the charge nurse and provider promptly, state that a mistake occurred, and ask how to solve the problem.

    The section emphasizes integrity, honesty, and accountability after a medication error. Promptly bringing the error to the charge nurse and provider allows a solution to be found more quickly and may prevent a bad outcome.

  2. A competent client refuses a prescribed medication after the nurse provides teaching. Which nursing actions are consistent with autonomy and the ANA Code of Ethics? Select all that apply.

    1. Support the client throughout the decision-making and treatment process.
    2. Respect the client’s decision after accurate and complete information has been provided.
    3. Attempt to persuade the client until they agree to take the medication.
    4. Tell the client they must take the medication because the provider ordered it.
    5. Explain the medication, including benefits and risks, in language the client can understand.

    Answer: Support the client throughout the decision-making and treatment process., Respect the client’s decision after accurate and complete information has been provided., Explain the medication, including benefits and risks, in language the client can understand.

    Autonomy means the client has the right to make informed, voluntary health care decisions, including refusal of a drug. The nurse may educate and support the client but should not coerce or pressure the client to accept treatment.

  3. A nurse is preparing to administer a prescribed medication but assessment findings suggest the medication is not safe for the client at this time. What is the best action by the nurse?

    1. Administer the medication because it has already been ordered.
    2. Ask the client whether they want to take the medication anyway.
    3. Give the medication and reassess the client later.
    4. Withhold the medication and notify the provider about the assessment findings.

    Answer: Withhold the medication and notify the provider about the assessment findings.

    The ANA Code of Ethics example for drug administration states that the nurse has accountability and responsibility to act when a medication appears unsafe. Withholding the medication and notifying the provider protects the client from potential harm.

  4. The nurse is reviewing events reported on a unit. Which events are medication errors according to the examples in this section? Select all that apply.

    1. A medication is administered to the wrong client.
    2. A client develops nausea after a correctly prescribed, dispensed, and administered medication.
    3. A client receives an extra dose of a medication.
    4. An extended-release tablet is crushed before administration.
    5. A client receives a medication despite a known allergen.

    Answer: A medication is administered to the wrong client., A client receives an extra dose of a medication., An extended-release tablet is crushed before administration., A client receives a medication despite a known allergen.

    The section lists extra dose, wrong client, known allergen, and crushing an extended-release tablet as medication errors. Nausea after a correctly used medication may be an adverse drug reaction rather than a medication error.

  5. A medication is administered to the wrong client, resulting in severe temporary harm. What institutional response is most consistent with this section?

    1. Wait to see whether the client recovers before reporting the event.
    2. Focus the investigation primarily on punishing the individual nurse.
    3. Report only to the client’s family because the event has already occurred.
    4. Report the event immediately so a root cause analysis can begin.

    Answer: Report the event immediately so a root cause analysis can begin.

    The section identifies wrong-client medication administration resulting in death or severe injury as a sentinel event. Sentinel events should be reported immediately so root cause analysis can identify underlying factors and help prevent recurrence.

  6. A client develops itching and a rash after receiving a medication at a normally used treatment dose, and no medication error is identified. Which interpretations or actions align with this section? Select all that apply.

    1. Report the adverse drug reaction through the available reporting mechanism.
    2. Classify the event as a medication error because all harmful medication events are errors.
    3. Recognize this as a possible adverse drug reaction.
    4. Recognize that a mild allergic reaction can cause itching and rash.
    5. Assume reporting is unnecessary unless the reaction is life-threatening.

    Answer: Report the adverse drug reaction through the available reporting mechanism., Recognize this as a possible adverse drug reaction., Recognize that a mild allergic reaction can cause itching and rash.

    The section defines adverse drug reactions as harmful, unintended reactions at normally used doses and notes that mild allergic reactions can cause itching and rash. It also states that nurses should report adverse drug reactions; these reactions affect safety but are not necessarily medication errors.

Where every quote comes from

Section 3.2 Drug Errors and Prevention of Pharmacology for Nurses by Tina Barbour-Taylor, Leah Mueller (Sabato), Donna Paris, Dorie Weaver, OpenStax, 2024. Read the whole section free at openstax.org.

The textbook is licensed under CC BY-NC-SA 4.0. This page quotes it word for word and adds the headings, the order and the practice questions; references to the book's figures and stray spaces left by its formatting are removed. The page is shared under the same licence. Nothing here is sold.