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Pharmacology · chapter 25 · Lower Respiratory Disorder Drugs

Corticosteroids

The 13 things this section of the textbook says that you are most likely to be asked about — quoted word for word, not retold. Then 6 practice questions with the reasoning.

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Key points

  1. What inhaled corticosteroids do

    These medications are designed to reduce inflammation and suppress the immune response in the airways (Cleveland Clinic, 2023a).
  2. Treating the underlying inflammation

    By targeting the underlying inflammation, corticosteroids help to control symptoms, prevent exacerbations, and improve lung function.
  3. Inhaled route limits systemic effects

    Inhaled corticosteroids are typically administered through inhalation devices directly into the lungs, allowing for targeted delivery to the respiratory system while minimizing systemic side effects.
  4. A cornerstone of long-term treatment

    They are considered a cornerstone of long-term respiratory treatment, often used in combination with other bronchodilators for optimal control (Williams, 2018).
  5. Common side effects

    Side effects of corticosteroid drugs include candidiasis (an oral fungal infection), hoarseness, cough, and increased susceptibility to infection.
  6. Never stop abruptly

    Clients should not stop corticosteroids abruptly because adrenal insufficiency may occur.
  7. Who should not use corticosteroids

    Those with hypersensitivity to the drug, systemic fungal infections, and recent live vaccines should not use corticosteroids.
  8. Potassium, sleep and weight

    Corticosteroids can affect potassium levels and sleep patterns, so both should be monitored during treatment. Corticosteroids can also cause weight gain, so weight should be monitored.
  9. Teach signs of infection

    Corticosteroids can modulate the immune system, so clients should be educated on signs and symptoms of infection to report (Cleveland Clinic, 2023a).
  10. Glucose in clients with diabetes

    Monitor glucose levels in clients with diabetes. Monitor for signs and symptoms of infection.
  11. Food with oral, rinse after inhaled

    Take oral corticosteroids with food to avoid gastrointestinal (GI) upset. Rinse mouth out after inhalation corticosteroids to reduce risk of candidiasis (thrush).
  12. Weight gain to report

    Report a weight gain of more than 2–3 pounds over 24 hours or 5 pounds in a week.
  13. Taper after long-term use

    From the book’s list of what the client should not do:

    Stop taking the drug abruptly because this can lead to adrenal insufficiency. Drug will need to be reduced gradually, especially after long-term therapy.

Terms to know

candidiasis
Side effects of corticosteroid drugs include candidiasis (an oral fungal infection), hoarseness, cough, and increased susceptibility to infection.

Practice questions

Stuck on select-all-that-apply? How to take them one option at a time.

The graded version needs JavaScript. Every question is below anyway, with the answer and why.

Every question here, with the answer

  1. A client who has taken prednisone for several months says they want to stop it because they feel better. What should the nurse teach?

    1. Do not stop it abruptly; the dose must be reduced gradually to avoid adrenal insufficiency.
    2. Switch to double doses on bad days only.
    3. Skip every other dose for a week, then stop.
    4. Stop it today since symptoms are controlled.

    Answer: Do not stop it abruptly; the dose must be reduced gradually to avoid adrenal insufficiency.

    Stopping corticosteroids abruptly can lead to adrenal insufficiency, so after long-term therapy the drug is reduced gradually. Stopping, skipping, or doubling doses on one's own is unsafe.

  2. A client using a fluticasone inhaler has white patches in the mouth. Which teaching point addresses this problem?

    1. Take the inhaler with food.
    2. Use the inhaler less often than prescribed.
    3. Rinse the mouth after each use of the inhaled corticosteroid.
    4. Use a second inhaler to wash the medicine down.

    Answer: Rinse the mouth after each use of the inhaled corticosteroid.

    Candidiasis, an oral fungal infection, is a side effect of corticosteroids, and rinsing the mouth after inhalation reduces the risk. Skipping doses is discouraged, and food is advised for oral, not inhaled, corticosteroids.

  3. A nurse is caring for a client taking oral prednisone. Which assessments should the nurse include? Select all that apply.

    1. Hearing acuity
    2. Potassium level
    3. Daily weight
    4. Sleep patterns
    5. Blood pressure

    Answer: Potassium level, Daily weight, Sleep patterns, Blood pressure

    The nurse monitors blood pressure, sleep patterns, potassium levels, and weight in clients taking corticosteroids. Hearing is not a listed assessment.

  4. A client taking prednisone weighs 2 pounds more today than yesterday and 5 pounds more than last week. What should the nurse tell the client?

    1. This weight gain should be reported to the health care provider.
    2. Weight gain is never related to corticosteroids.
    3. Weigh yourself only once a month.
    4. Stop the prednisone to lose the weight.

    Answer: This weight gain should be reported to the health care provider.

    Clients report a weight gain of more than 2–3 pounds over 24 hours or 5 pounds in a week, and weight gain is a known corticosteroid effect. Stopping the drug abruptly is unsafe, and clients weigh themselves daily.

  5. Which clients should NOT receive a corticosteroid? Select all that apply.

    1. A client with COPD
    2. A client with asthma
    3. A client with a systemic fungal infection
    4. A client with hypersensitivity to the drug
    5. A client who just received a live vaccine

    Answer: A client with a systemic fungal infection, A client with hypersensitivity to the drug, A client who just received a live vaccine

    Clients with hypersensitivity, systemic fungal infections, or recent live vaccines should not use corticosteroids. Asthma and COPD are the conditions corticosteroids are used to treat.

  6. A client with type 2 diabetes is starting oral prednisone. Which teaching is most important?

    1. Take prednisone on an empty stomach.
    2. Avoid wearing a medical ID bracelet.
    3. You no longer need to check your blood glucose.
    4. Monitor your blood glucose carefully.

    Answer: Monitor your blood glucose carefully.

    Clients with diabetes taking corticosteroids should monitor glucose carefully, and hyperglycemia is a listed adverse effect. Oral corticosteroids are taken with food, and a medical ID bracelet is recommended.

Where every quote comes from

Section 25.2 Corticosteroids of Pharmacology for Nurses by Tina Barbour-Taylor, Leah Mueller (Sabato), Donna Paris, Dorie Weaver, OpenStax, 2024. Read the whole section free at openstax.org.

The textbook is licensed under CC BY-NC-SA 4.0. This page quotes it word for word and adds the headings, the order and the practice questions; references to the book's figures and stray spaces left by its formatting are removed. The page is shared under the same licence. Nothing here is sold.