Fundamentals · chapter 19 · Oxygenation and Perfusion
Cardiovascular System
The 14 things this section of the textbook says that you are most likely to be asked about — quoted word for word, not retold. Then 6 practice questions with the reasoning.
Key points
Perfusion enables oxygenation
Without the cardiovascular system, gas exchange would not be useful, as perfusion is necessary for O 2 and other nutrients to be distributed throughout the body and reach the tissues.
Cardiac chamber flow
The heart consists of four chambers: two atria and two ventricles. The right atrium receives deoxygenated blood from systemic circulation, and the left atrium receives oxygenated blood from the lungs.
Ventricular pumping roles
The atria contract to push blood into the lower chambers, the right ventricle, and the left ventricle. The right ventricle contracts to push blood into the lungs, and the left ventricle is the primary pump that propels blood to the rest of the body.
Coronary perfusion timing
Another distinctive property is the heart’s own circulation: coronary arteries perfuse the cardiac muscle itself, and this blood flow is primarily supplied during diastole.
Venous valve function
Larger veins are also equipped with a valve that promote the unidirectional flow of blood toward the heart and prevent backflow caused by the inherent low blood pressure in veins as well as the pull of gravity.
Intravascular volume and pressure
The amount of fluid within the blood vessels, or intravascular volume, contributes to blood pressure as measured by pressure within the arteries.
Cardiac output meaning
Another concept is that of cardiac output (CO), which is the amount of blood pumped by the left ventricle in one minute.
Pulmonary and systemic circuits
The pulmonary circuit transports blood to and from the lungs, where it picks up oxygen and delivers carbon dioxide for exhalation. The systemic circuit transports oxygenated blood to virtually all of the tissues of the body and returns deoxygenated blood and carbon dioxide to the heart to be sent back to the pulmonary circulation.
Vascular disease pressure effects
Arteriosclerosis lessens the elastic properties of blood vessels and, therefore, the ability for vasodilation, which increases the intravascular pressure. Atherosclerosis narrows the internal space of blood vessels, which also increases the pressure within the intravascular space.
Hypovolemia perfusion signs
The loss of volume means less fluid volume in the circulatory system, which is typified by a low BP, manifested by signs and symptoms of low perfusion, such as mental status changes ranging from slight confusion to, potentially, seizure, cool and clammy skin, low urine output, climbing creatinine, and other laboratory results illustrating a concentrated sample.
Stroke volume determinants
Three primary factors that affect SV are preload, or the stretch on the ventricles prior to contraction; contractility, or the force or strength of the contraction itself; and afterload, the force the ventricles must generate to pump blood against the resistance in the vessels.
Ejection fraction ranges
Normal EF is approximately 50 to 70 percent; it is therefore considered preserved if it is over 50 percent (Bruss Raja, 2022). Reduced EF is indicated when there are clinical manifestations of HF and the EF is at or under 40 percent.
Cardiovascular receptor regulation
Baroreceptors are specialized stretch receptors located in the aorta and carotid arteries that respond to the degree of stretch caused by the presence of blood and then send impulses to the cardiovascular center to regulate BP. In addition to the baroreceptors, chemoreceptors monitor levels of oxygen, carbon dioxide, and pH.
Normal sinus rhythm criteria
Criteria for normal sinus rhythm include that the impulse begins at the SA node, travels from the SA node to the atrioventricular (AV) node in 0.12 seconds or less, and has a rate between 60 and 100 beats per minute.
Terms to know
- mediastinum
- The human heart is located within the thoracic cavity, medially between the lungs in the space known as the mediastinum.
- artery
- An artery is a blood vessel that carries blood away from the heart, where it branches into ever-smaller vessels and eventually into tiny capillaries where nutrients and wastes are exchanged at the cellular level.
- vein
- Capillaries combine with other small blood vessels that carry blood to a vein, a larger blood vessel that returns blood to the heart.
- intravascular volume
- The amount of fluid within the blood vessels, or intravascular volume, contributes to blood pressure as measured by pressure within the arteries.
- cardiac output (CO)
- Another concept is that of cardiac output (CO), which is the amount of blood pumped by the left ventricle in one minute.
- stroke volume (SV)
- The amount of blood expelled from the left ventricle during a single systolic contraction is known as stroke volume (SV).
- ejection fraction (EF)
- The ejection fraction (EF) is the percentage of blood within the ventricle that is expelled during a single systolic contraction.
- baroreceptors
- Baroreceptors are specialized stretch receptors located in the aorta and carotid arteries that respond to the degree of stretch caused by the presence of blood and then send impulses to the cardiovascular center to regulate BP.
Practice questions
Stuck on select-all-that-apply? How to take them one option at a time.
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Every question here, with the answer
A student is reviewing heart anatomy before listening to heart sounds. Which statement about the base of the heart is accurate?
- It is the superior surface of the heart, where the great veins and great arteries attach
- It is the middle layer of the heart, made of cardiac muscle cells
- It is the inferior tip of the heart
- It is the chamber that receives oxygenated blood from the lungs
Answer: It is the superior surface of the heart, where the great veins and great arteries attach
The great veins (superior and inferior venae cavae) and great arteries (aorta and pulmonary trunk) attach to the superior surface of the heart, called the base. The inferior tip is the apex, the muscle layer is the midlayer, and the left atrium receives oxygenated blood from the lungs.
A patient has fluid loss after exertion in hot weather. Which findings would the nurse recognize as consistent with hypovolemia and low perfusion? Select all that apply.
- Cool and clammy skin
- Low urine output
- Laboratory results illustrating a concentrated sample
- Warm, dry skin with increased vascular volume
- Mental status changes ranging from slight confusion to seizure
Answer: Cool and clammy skin, Low urine output, Laboratory results illustrating a concentrated sample, Mental status changes ranging from slight confusion to seizure
Hypovolemia means less fluid volume in the circulatory system and is associated with signs of low perfusion, including mental status changes, cool clammy skin, low urine output, and concentrated laboratory results. Increased vascular volume is more consistent with hypervolemia, not hypovolemia.
A patient’s heart rate is very fast. The nurse is concerned that cardiac output may not be maintained if the rate continues to increase. What is the best physiological explanation?
- The coronary arteries supply blood only during systole
- The ventricles may not have enough time for adequate filling, reducing stroke volume
- The systemic circuit stops returning deoxygenated blood to the heart
- The left atrium stops receiving oxygenated blood from the lungs
Answer: The ventricles may not have enough time for adequate filling, reducing stroke volume
When heart rate becomes too fast, stroke volume can decrease because ventricular filling time is insufficient. The section describes tachycardia as temporarily compensatory, but too rapid a rate can impair stroke volume.
A patient is experiencing sympathetic nervous system stimulation during acute stress. Which responses would the nurse expect based on cardiovascular regulation? Select all that apply.
- Bronchoconstriction with lower blood pressure
- Increased heart rate and blood pressure
- Bronchodilation
- Pupillary dilation
- Glucose release
Answer: Increased heart rate and blood pressure, Bronchodilation, Pupillary dilation, Glucose release
The sympathetic nervous system is associated with fight-or-flight responses such as bronchodilation, pupillary dilation, glucose release, and increased HR and BP. Bronchoconstriction and lower BP are listed as parasympathetic-associated responses.
A nurse is teaching a patient why valves in larger veins are important for circulation. Which explanation is most accurate?
- They help blood move toward the heart and prevent backflow
- They exchange nutrients and wastes at the cellular level
- They carry blood away from the heart under high pressure
- They provide the primary blood supply to cardiomyocytes
Answer: They help blood move toward the heart and prevent backflow
Larger veins have valves that support one-way movement of blood toward the heart and help prevent backflow, especially because veins are low-pressure vessels affected by gravity. Capillaries exchange nutrients and wastes, arteries carry blood away from the heart, and coronary arteries perfuse cardiomyocytes.
A nurse is reviewing an ECG rhythm strip and determining whether it meets criteria for normal sinus rhythm. Which criteria should the nurse use? Select all that apply.
- The rate is between 60 and 100 beats per minute
- The impulse begins at the SA node
- The rhythm is identified only by specialized testing used to obtain stroke volume
- The AV node initiates the impulse because the SA node does not fire
- The impulse travels from the SA node to the AV node in 0.12 seconds or less
Answer: The rate is between 60 and 100 beats per minute, The impulse begins at the SA node, The impulse travels from the SA node to the AV node in 0.12 seconds or less
Normal sinus rhythm requires that the impulse start in the SA node, travel to the AV node in 0.12 seconds or less, and have a rate of 60 to 100 beats per minute. AV-node initiation is a backup mechanism if the SA node does not fire, and stroke volume testing is unrelated to the criteria for normal sinus rhythm.
Where every quote comes from
Section 19.2 Cardiovascular System of Fundamentals of Nursing by Christy Bowen, Lindsay Draper, Heather Moore, OpenStax, 2024. Read the whole section free at openstax.org.
The textbook is licensed under CC BY-NC-SA 4.0. This page quotes it word for word and adds the headings, the order and the practice questions; references to the book's figures and stray spaces left by its formatting are removed. The page is shared under the same licence. Nothing here is sold.